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44 Biotechnology / Life Sciences jobs in Rochdale

Research Associate (Grade...

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The University of Manchester, City Centre, Manchester

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Posted 2 days ago, 26 May

Compliance Risk Assessmen...

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The Bank of New York Mellon Corporation, City Centre, Manchester

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Posted 2 days ago, 26 May

Biomedical Scientist Cell...

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Bolton Nhs Foundation Trust, Dixon Green, Bolton

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Posted 3 days ago, 25 May

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Aseptic Services Technici...

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The Christie NHS Foundation Trust, Withington, Manchester

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Posted 3 days ago, 25 May

Head of Orthodontics UK

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Straumann, Stockport

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Posted 3 days ago, 25 May

Territory Sales Manager

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Stryker UK Limited, City Centre, Manchester

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Posted 4 days ago, 24 May

Territory Sales Manager

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Stryker UK Limited, The Wrangling, Blackburn with Darwen

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Posted 4 days ago, 24 May

Territory Sales Manager

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Stryker UK Limited, Scaitcliffe, Hyndburn

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Posted 4 days ago, 24 May

Senior/ Clinical Research...

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The Christie NHS Foundation Trust, City Centre, Manchester

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Posted 4 days ago, 24 May

Sales Business Manager, T...

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Stryker UK Limited, City Centre, Manchester

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Posted 4 days ago, 24 May

Territory Sales Manager

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Stryker UK Limited, Burnley

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Posted 4 days ago, 24 May

Field Sales Specialist

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Mettler Toledo, City Centre, Manchester

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Posted 4 days ago, 24 May

Senior Process Engineer- ...

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Arup, City Centre, Manchester

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Posted 5 days ago, 23 May

Senior Medical Writer

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Springer, City Centre, Manchester

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Posted 5 days ago, 23 May

Haematology Technical Man...

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Northern Care Alliance NHS Foundation Trust, Rhodes Bank, Oldham

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Posted 5 days ago, 23 May

Inside Sales Representati...

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Agilent Technologies, Inc., Cheadle, Stockport

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Posted 5 days ago, 23 May

4 year PhD Studentship: D...

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University of Nottingham, City Centre, Manchester

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Posted 5 days ago, 23 May

PhD Studentship - Crossli...

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The University of Manchester, City Centre, Manchester

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Posted 5 days ago, 23 May

PhD Studentship - Lithium...

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The University of Manchester, City Centre, Manchester

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Posted 5 days ago, 23 May

Scientific Services Direc...

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Springer, City Centre, Manchester

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Posted 5 days ago, 23 May
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Research Associate (Grade 6) or Research Fellow (Grade 7) in The Development and Application Of New Mass Spectrometry Methods To Characterise Virus Based Drug Products

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The University of Manchester, City Centre, Manchester

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  • Full time
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Posted 2 days ago, 26 May

Job ref: 12c61b66a12349479d30eb60d77efb20

Full Job Description

In this project we seek a motivated individual, with extensive mass spectrometry experience, who wants to develop a new instrument and apply it to the study of MDa. protein assemblies. You will be based in the team of Prof. Perdita Barran in the Michael Barber Centre for Collaborative Mass Spectrometry, and work closely with Dr. John Hoyes (TrueMass Ltd.), Dr. Dimitris Papamastasiou (Fasmatech Ltd.) and Prof. Rob Appleby (UoM). Your primary role will be to build, install and test a new geometry CDMS instrument with a novel ESI source with improved characteristics for the transmission of MDa ions The project also involves close collaboration with Prof. Brian Biggar (UoEdindburgh) and collaborators at Pharmaron ltd. as we apply the technology to determine the DNA content of recombinant adenoassociated viral (AAV) vectors. We propose to compare the capabilities of this instrument with that of commercially available mass spectrometry platforms and other methods. As part of this exciting and truly interdisciplinary project you will also build a stage to allow subsequent characterisation of these MDa. complexes via microscopy. You will develop standard operating procedures for the instrument using, large assembled protein standards (ferritin, Groel and IgEs) and subsequently develop its use for AAVs. The potential to study other large assemblies will also be explored especially heavily glycosylated protein assemblies. This project will use the instrument to measure how many of a given AAV product have filled capsids versus empty and we will compare the data to the efficacy of the drug in animal models. What can you expect in return The University will actively foster a culture of inclusion and diversity and will seek to achieve true equality of opportunity for all members of its community.

What you will get in return:

  • Fantastic market leading Pension scheme
  • Excellent employee health and wellbeing services including an Employee Assistance Programme
  • Exceptional starting annual leave entitlement, plus bank holidays
  • Additional paid closure over the Christmas period
  • Local and national discounts at a range of major retailers
    • As an equal opportunities employer we welcome applicants from all sections of the community regardless of age, sex, gender (or gender identity), ethnicity, disability, sexual orientation and transgender status. All appointments are made on merit. Our University is positive about flexible working - you can find out more Hybrid working arrangements may be considered Please note that we are unable to respond to enquiries, accept CVs or applications from Recruitment Agencies. Any CV's submitted by a recruitment agency will be considered a gift. Enquiries about the vacancy, shortlisting and interviews: Name: Name: Perdita Barran Email: General enquiries: Email: Technical support: This vacancy will close for applications at midnight on the closing date. Please see the link below for the Further Particulars document which contains the person specification criteria.

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