Postdoctoral Researcher; Neurotropic viruses in Alzheimer's disease

We are seeking a motivated and ambitious Postdoctoral Researcher to join an exciting multidisciplinary research programme investigating the relationship between neurotropic viral infections and Alzheimer's disease. Emerging epidemiological and experimental evidence suggests that neurotropic viral infections, including herpes viruses, influenza and SARS-CoV-2, may be associated with an increased risk of developing Alzheimer's disease.
These viruses may contribute to disease progression by increasing amyloid beta and tau levels, promoting inflammation and inducing cell death. Herpes viruses can also establish latent infections, which may further contribute to Alzheimer's disease pathology, particularly in individuals carrying the APOE E4 genetic risk variant.
Your research will focus on defining the mechanisms through which neurotropic viruses contribute to Alzheimer's disease pathology in neurons and glial cells, while investigating how different APOE genotypes influence these processes. You will take responsibility for managing your own academic research and associated administrative activities, coordinating multiple aspects of the project and ensuring that research objectives and deadlines are successfully met. You will contribute ideas for new research projects and have the opportunity to adapt existing scientific methods as well as develop new techniques and experimental protocols.

It is essential that you hold a relevant PhD/DPhil in virology or related sciences with relevant research experience. You must have experience in virology and working with containment level 2 pathogens. Experience in general molecular biology techniques and cell biology is must.

Centre for Human Genetics, Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN

Applications for this vacancy should be made online and you will need to upload a supporting statement and CV. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience. Please restrict your documentation to your CV and supporting statement only. Any other documents will be requested at a later date.