We are seeking a postdoctoral bioinformatician to join Dr. Progatzky's interdisciplinary laboratory for an exciting opportunity focused on cell-atlasing. This role aims to uncover systems-level insights into human peripheral glia across barrier organs in both health and disease. You will collaborate with the Dendrou lab at the Kennedy Institute and also the Haniffa lab at Sanger Institute. You will analyse large-scale single-cell and spatial genomics datasets, generating novel insights into peripheral glial biology providing and hypothesis for experiments conducted in the lab. Working closely with the wet lab team, you will help identify key regulatory mechanisms for functional validation, fostering hypothesis-driven translational research.
You will develop, tailor, and implement methodologies, tools, and informatics structures for data analysis and management in collaboration with the research team. Additionally, you will provide guidance to laboratory and biostatistical staff, assisting with project-related tasks as needed.

You must hold a PhD either in Bioinformatics, Statistics, Mathematics, Computer Science, or a related computational field with demonstrated relevance to tissue biology or immunology-particularly in the context of inflammatory diseases-or a PhD in Immunology, Tissue Biology, or a related biomedical field with substantial experience in bioinformatics, computational analysis, or statistical modeling relevant to these areas. You will have proven experience in genomics, high-throughput data processing, and analysis, with specific expertise in single-cell RNA-seq and spatial transcriptomics data (e.g., 10X Genomics platforms). Experience with High-Performance Computing (HPC) and/or cloud computing is desirable.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Kennedy Institute of Rheumatology, Roosevelt Drive, Headington, Oxford OX3 7FY

This is a full-time fixed-term appointment for 3 years., A lower grade offer (Grade 7: £38,674 - £46,913 p.a.) may be made to a less experienced candidate if a suitable candidate cannot be found to fill the Grade 8 position.