Research Fellow in Autoimmune Disease

We are seeking to employ a Research Fellow in Autoimmune with a background in immunology and a research interest in autoimmune diseases to conduct research into the rare autoimmune disease Thrombotic Thrombocytopenic Purpura (TTP). This life-threatening disorder is characterized by autoantibodies against the enzyme ADAMTS13, which ultimately lead to thrombotic occlusion of the microvasculature. The research project will focus on investigating patient B-cells and T-cells that are specific for the autoantigen (ADAMTS13).

The Research Fellow will develop and plan research together with Prof Scully and Dr de Groot and carry out the research in accordance with agreed projects as well as conducting data analysis ensuring its validity and reliability of data at all times.

The Research Fellow must have a PhD in immunology, a research interest in autoimmune disease and experience with isolating PBMC's and investigating lymphocytes. The role holder will also be skilled in flow cytometry.

The Haemostasis Research Unit (HRU) is a vibrant research group that consists of clinicians and basic scientists conducting world leading research on the autoimmune disease Thrombotic Thrombocytopenic Purpura (TTP). The research unit, based in Bloomsbury, is led by Prof Marie Scully and Dr Rens de Groot and hosts the UK TTP registry. The clinicians run the TTP specialist centre at UCLH for the Southeast of England. The laboratory is part of the Institute of Cardiovascular Science, which is a world-class centre of excellence focussed on developing novel preventative and therapeutic strategies in cardiovascular medicine., Our Institute holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality

The post is full-time (36.5 hours) and funded until 30th November 2027. Further funding may become available.

Appointment at Grade 7 (£42,099 - £50,585 per annum) is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (£37,332 - £39,980 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.,

• 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)


• Additional 5 days' annual leave purchase scheme


• Defined benefit career average revalued earnings pension scheme (CARE)


• Cycle to work scheme and season ticket loan


• Immigration loan


• Relocation scheme for certain posts


• On-Site nursery


• On-site gym


• Enhanced maternity, paternity and adoption pay


• Employee assistance programme:Staff Support Service


• Discounted medical insurance